Joined Mar 21 2015
37 years old
University of California Riverside
Biological signaling occurs at different levels, but basic processes are largely chemically based. Our research team at UC Riverside is engineering novel molecular probes to peer into cells and brains to understand their communications. We use a collection of innovative techniques, such as protein engineering, fluorescence and bioluminescence imaging, synthetic chemistry and mass spectrometry, to dissect signaling pathways involving redox-active molecules, neurotransmitters, and protein post-translational modifications (PTMs). Our immediate goal is to monitor biological signaling in real time with excellent spatial resolution and molecular precision in physiologically relevant environments. Our long-term goal is to apply these new probes to live cells (including stem cells) and animal models to understand communications relevant to toxicity of chemicals, cancer development and progression, cognition and behavior, and neurological disorders.